Anesthesia for and analgesia after in-utero repair of myelomeningocele

Biro P

Journal: Nesa Days 2015

Date: 01/09/2015

Institute of Anesthesiology, University Hospital Zurich, CHF 8091 Zurich, Switzerland

Perinatal outcome of our first 20 cases after open fetal myelomeningocele repair at the Zurich Center for Fetal Diagnosis and Therapy

U Moehrlen 1, 2, N Ochsenbein 2, 3, M Huesler 2, 3, P Biro 2, 4, I Scheer 2, 5, L Mazzone 1, 2, R Zimmermann 2, 3, M Meuli 1, 2

After the MOMS trial was published in 2010, open fetal surgery is considered the standard treatment for selected fetuses with Myelomeningocele (MMC) in experienced hands. We report our data on perinatal outcome of the first 20 in utero operated fetuses.

Journal: Thieme Zeitschrift für Geburtshilfe und Neonatologie 2015; 219 - FV09_6

Date: 01/01/2015

1 Universitäts Kinderspital Zürich, Chirurgische Klinik, Zürich, Switzerland

2 Zentrum für fetale Diagnostik und Therapie Zürich, Zürich, Switzerland

3 UniversitätsSpital Zürich, Klinik für Geburtshilfe, Zürich, Switzerland

4 UniversitätsSpital Zürich, Klinik für Anästhesiologie, Zurich, Switzerland

5 Universitäts Kinderspital Zürich, Radiologie, Zürich, Switzerland

Experimental tissue engineering of fetal skin

L Mazzone  1 , L Pontiggia, E Reichmann, N Ochsenbein-Kölble, U Moehrlen, M Meuli

In some human fetuses undergoing prenatal spina bifida repair, the skin defect is too large for primary closure. The aim of this study was to engineer an autologous fetal skin analogue suitable for in utero skin reconstruction during spina bifida repair.

Journal: Pediatric Surgery International (2014) 30:1241-1247 - published online: 22 October 2014

Date: 22/10/2014

1 Department of Surgery, University Children's Hospital Zurich, Zurich, Switzerland,

Assessment of long-term donor-site morbidity after harvesting the latissimus dorsi flap for neonatal myelomeningocele repair

R Osinga  1 , L Mazzone  2 , M Meuli  2 , C Meuli-Simmen  3 , A von Campe  3               

The latissimus dorsi flap (LDF) has been employed very successfully over decades to cover large soft-tissue defects. Its donor-site morbidity has been extensively investigated in adults - but not in children - and is considered to be nonrestrictive. The aim of this long-term study was to assess donor-site morbidity with the modified Constant score more than 8 years after coverage of large myelomeningocele (MMC) defects with a reverse latissimus dorsi flap.

Journal: Journal of Plastic, Reconstructive and Aesthetic Surgery - published online May 2, 2014

Date: 01/08/2014

1 Clinic of Hand, Reconstructive and Plastic Surgery, Kantonsspital Aarau, Aarau, Switzerland. Electronic address:

2 Department of Pediatric Surgery, University Children's Hospital Zurich, Zurich, Switzerland.

3 Clinic of Hand, Reconstructive and Plastic Surgery, Kantonsspital Aarau, Aarau, Switzerland.

Fetal surgery for myelomeningocele is effective: a critical look at the whys

Martin Meuli 1, Ueli Moehrlen

Formerly, the disastrous cluster of neurologic deficits and associated neurogenic problems in patients with myelomeningocele (MMC) was generally thought to solely result from the primary malformation, i.e., failure of neurulation.

Journal: Springer Pedicatric Surgery International - Published online: 8 June 2014

Date: 01/07/2014

1. Department of Pediatric Surgery, University Children's Hospital Zurich, Steinwiesstrasse 75, 8032, Zurich, Switzerland,